Your Skin Microbiome Consultation

Answer six short questions to discover an ISUN skincare ritual tailored to your skin's unique needs and informed by our microbiome-friendly approach to skin health.

Question 1 of 6

01 / 06 · Skin Type

How does your skin naturally feel throughout the day?

Think about your skin a few hours after your morning routine, before applying anything else. This often reveals your skin's natural tendencies.

02 / 06 · Primary Concern

What concerns you most about your skin at this moment?

Select all that apply.

If more than one applies, choose the concern that feels most important to you.

03 / 06 · Duration

How long has this been present?

The duration of a concern can provide helpful context when selecting products and building a skincare ritual.

04 / 06 · Lifestyle

How would you describe your typical stress levels and sleep habits?

Skin is influenced by many aspects of well-being, including rest, daily stress, and lifestyle. Understanding these patterns helps us personalize your recommendations.

05 / 06 · Sun Protection

Do you wear SPF every day?

Daily sun protection helps support skin health and is an important part of maintaining a radiant, healthy-looking complexion.

06 / 06 · Your Routine

How would you describe your current skincare routine?

Every skincare ritual is different. Understanding yours helps us personalize our recommendations to your skin's needs.

Your Skin Care Routine

Based on your responses, these are the ISUN formulations the science identifies as most aligned with your skin's biology.

Your Skin Profile

Primary Formulations

Supporting Formulations

1M+
Microbial species call your skin home
4
Four criteria used to evaluate microbiome compatibility
11
Isun formulas meet our microbiome compatibility framework
ISUN Skincare
Rooted in nature, grounded in science

Section 01

What Is the Skin Microbiome

A Living System, In Constant Balance

Your skin is more than a surface. It is a living ecosystem, home to billions of microorganisms that exist alongside your skin every day.

Together, these bacteria, fungi and other microbes form what is known as the skin microbiome. This complex community plays an important role in helping maintain the skin barrier, supporting hydration and contributing to healthy-looking, resilient skin.

Like any ecosystem, the skin microbiome thrives when balance is maintained. When this balance is disrupted, skin may appear less comfortable, less resilient and more prone to visible changes in its appearance.

Research continues to deepen our understanding of the microbiome and its connection to skin health. What is becoming increasingly clear is that healthy skin is not sterile skin. A balanced skin ecosystem is an important part of the skin’s natural function.

ISUN Phyto-Infusion Serum — a generation 2 microbiome serum

Current research suggests that healthy skin is supported by a diverse and balanced microbiome. Rather than attempting to eliminate microorganisms, modern skincare increasingly focuses on supporting the conditions that allow the skin's natural ecosystem to thrive.

Byrd et al. (2018); Han & Kim (2024)
Probiotics

Probiotics

Supporting from Within

Probiotic-derived ingredients and fermented extracts help support the skin’s natural barrier and healthy microbiome, promoting overall skin wellness.

Commonly found in fermented ingredients, lysates, and postbiotic skincare formulations.

Prebiotics

Prebiotics

Nourishing What Exists

Ingredients such as beta-glucan and plant-derived sugars that help support a healthy skin environment and the skin’s natural microbiome.

Postbiotics

Postbiotics

Bioactive by Nature

Beneficial compounds created during fermentation that help support skin hydration, comfort, and barrier function. Known for their stability and compatibility in skincare formulations.

Microbiome Friendly

Microbiome-Friendly

Formulated for Balance

Designed to support the skin’s natural microbiome and protective barrier. These formulations help maintain hydration, balance, and skin comfort while working in harmony with the skin’s natural functions.


ISUN Phyto-Antioxidant — best overall microbiome formula

Section 02

Why the Microbiome Matters

Balance, Reflected in the Skin

The skin microbiome plays an important role in maintaining healthy-looking skin.

When this living ecosystem is balanced, skin often appears calmer, more resilient and naturally radiant. The skin barrier is better able to maintain moisture, and the skin is better equipped to respond to everyday environmental stressors.

When balance is disrupted, the skin may become less comfortable and more prone to visible changes in its appearance. Research continues to explore the relationship between the skin microbiome and concerns such as breakouts, sensitivity, redness, uneven skin tone and visible signs of skin aging.

A microbiome-conscious approach focuses on supporting the skin’s natural ecosystem. By helping maintain barrier integrity, hydration balance and skin comfort, skincare can work in harmony with the skin’s natural processes.

Acne & Breakouts

Breakouts

When Balance Is Disrupted

Changes in the skin's natural balance may contribute to the appearance of breakouts and congestion.

Supporting the skin barrier and microbiome can help maintain a clearer, healthier-looking complexion over time.¹

Sensitivity

Sensitivity

When Comfort Is Compromised

When the skin barrier is weakened, skin may become more reactive and prone to discomfort from everyday stressors.

Supporting barrier strength and hydration balance can help improve skin comfort and resilience over time.²

Redness

Redness

When Skin Feels Out of Balance

Visible redness can occur when the skin barrier becomes stressed or the skin's natural balance is disrupted.

Nourishing botanicals and supportive lipids help comfort the skin and promote a calmer, more balanced appearance.²

Signs of Aging

Visible Signs of Skin Aging

Supporting Skin Vitality

Over time, changes in the skin's natural environment can contribute to visible signs of aging, including dryness, loss of radiance and reduced elasticity.

Supporting the skin barrier, maintaining hydration and nourishing the skin with nutrient-rich botanicals can help promote a healthier, more vibrant-looking complexion.³

Barrier Integrity

Barrier Integrity

The Foundation of Healthy-Looking Skin

The skin barrier and microbiome work together to help protect and support the skin.

When the skin barrier is strong and balanced, skin is better able to retain moisture, maintain comfort and support overall resilience.

Uneven Skin Tone

Uneven Skin Tone

Supporting Natural Radiance

A healthy skin environment helps support the skin's natural renewal process and overall appearance.

When hydration and barrier balance are maintained, skin often appears brighter, smoother and more even-toned.²

Section 03

What Supports a Healthy Skin Ecosystem

Ingredients Chosen for Balance and Resilience

Research into the skin microbiome continues to evolve, and many ingredients are being studied for their role in supporting a healthy skin environment. A healthy-looking complexion depends on more than a single ingredient. It is supported by a combination of barrier-supporting lipids, nourishing botanicals, fermented ingredients and hydration-supportive actives that work together to help maintain balance. At ISUN, we formulate with nutrient-rich botanicals, supportive plant oils and natural actives selected to work in harmony with the skin's natural processes.

Barrier-Supporting Oils

Supporting the Skin's Foundation

The skin barrier and skin ecosystem are closely connected. Plant oils rich in essential fatty acids help support the skin barrier, maintain moisture and contribute to healthy-looking skin.

Nourishing Botanicals

Helping Maintain Balance

Botanical extracts rich in antioxidants and plant compounds help support skin comfort, resilience and overall skin well-being.

Fermented Ingredients

Supporting Skin Vitality

Fermentation-derived ingredients provide naturally occurring compounds that help support hydration, skin comfort and barrier integrity.

The Ingredients Behind Every Formula

Documented, Purposeful

Transparency is part of the ISUN philosophy. Every ingredient featured below is included with intention, selected for its unique properties and the role it plays within the overall formulation.

Barrier Oil

Jojoba Oil

Simmondsia Chinensis Seed Oil

Rich in wax esters that closely resemble the skin’s natural lipids, helping support skin comfort and barrier integrity.

Vollmer et al. (2018), IJMS

Barrier Oil

Sunflower Seed Oil

Helianthus Annuus Seed Oil

Naturally rich in linoleic acid, helping support the skin barrier and maintain healthy-looking skin.

Siqueira et al. (2025), ACS Omega

Barrier Oil

Sea Buckthorn Oil

Hippophae Rhamnoides Oil

Contains naturally occurring fatty acids that help nourish the skin and support skin comfort.

Siqueira et al. (2025), ACS Omega

Barrier Oil

Rosehip Oil

Rosa Canina / Rubiginosa Seed Oil

Provides essential fatty acids and naturally occurring plant compounds that help support skin nourishment and barrier integrity.

Vollmer et al. (2018), IJMS

Botanical

Green Tea Extract

Camellia Sinensis Leaf Extract

Rich in antioxidant compounds that help protect the skin from environmental stressors and support healthy-looking skin.

Melnyk et al. (2022), IJMS

Botanical

Licorice Root

Glycyrrhiza Glabra Root Extract

Traditionally used to support a brighter, more even-looking complexion and overall skin comfort.

Melnyk et al. (2022), IJMS

Botanical

Calendula & Helichrysum

Calendula Officinalis · Helichrysum Italicum

Botanical extracts valued for their soothing properties and ability to support healthy-looking skin.

De Almeida et al. (2023), Microorganisms

Fermented

yeast cell extract

Saccharomyces Lysate Extract

Fermentation-derived ingredient used throughout selected ISUN formulations. Provides naturally occurring compounds that help support hydration, skin comfort, and barrier integrity.

De Almeida et al. (2023), Microorganisms

Hydration

Beta-Glucan

Beta-Glucan

Helps support hydration, skin comfort, and overall skin resilience.

Zeng et al. (2025), Antioxidants

Hydration

Hyaluronic Acid

Sodium Hyaluronate

Helps attract and retain moisture, supporting hydration balance and skin comfort.

Zeng et al. (2025), Antioxidants

Hydration

Aloe Vera

Aloe Barbadensis Leaf Juice

Provides hydration and soothing plant compounds that help support skin comfort and overall skin well-being.

Wojciechowska & Dos Santos Szewczyk (2025), Molecules

Active

Niacinamide

Niacinamide (Vitamin B3)

A versatile active that supports an even-looking skin tone, helps reinforce the barrier, and is well-tolerated across a range of skin types including sensitive skin.

Melnyk et al. (2022), IJMS

Barrier Oil

Ceramide NP

Ceramide NP

A skin-identical lipid that reinforces the protective barrier layer, helps reduce transepidermal water loss, and supports a balanced, resilient skin surface.

Meckfessel & Brandt (2014), JAAD

Hydration

Pentavitin®

Saccharide Isomerate

A plant-derived humectant that binds moisture to the skin's own carbohydrate receptors, providing long-lasting hydration without disrupting the skin's natural balance.

Zeng et al. (2025), Antioxidants

Active

Vitamin C

Sodium Ascorbyl Phosphate · Ascorbyl Glucoside

Stable vitamin C derivatives that support an even-looking complexion, provide antioxidant protection, and contribute to a bright, healthy-looking skin appearance.

Melnyk et al. (2022), IJMS

A note on essential oils and antimicrobial actives: Some natural ingredients — including certain essential oils — have antimicrobial properties that can affect microbial populations at high concentrations. ISUN formulations use botanical extracts thoughtfully and at levels designed for skin compatibility. This is not a reason to avoid these ingredients; rather, it reflects the importance of formulation context, concentration, and how ingredients work together in a complete product.

Science References

  • Han & Kim (2024). J. Microbiology — Skin microbiome and acne dysbiosis.
  • Hong et al. (2025). Annals of Dermatology — Microbiome links to eczema, rosacea and inflammatory conditions.
  • Townsend & Kalan (2023). Biochem. Soc. Trans. — Age-related microbiome diversity decline and skin aging.
  • Smythe & Wilkinson (2023). IJMS — Barrier repair as the primary microbiome stabilizer.
  • Siqueira et al. (2025). ACS Omega; Vollmer et al. (2018) IJMS — Barrier oils and microbiome habitat.
  • Melnyk et al. (2022). IJMS; Mourelle et al. (2023) Appl. Sci. — Anti-inflammatory botanicals and microbiome stability.
  • De Almeida et al. (2023). Microorganisms — Postbiotics and fermented ingredients in skincare. Roman et al. (2025). Molecules — Calendula, Helichrysum, and botanical skin-support activity.
  • Byrd, Belkaid & Segre (2018). Nature Reviews Microbiology — The human skin microbiome.
  • Meckfessel & Brandt (2014). JAAD — The structure, function, and importance of ceramides.
  • Zeng et al. (2025). Antioxidants — Beta-glucan, hyaluronic acid, and hydration network components.

Section 04

ISUN Microbiome-Aligned Formulations

Defined by Science, Selected with Intention

Each ISUN formulation is evaluated against four criteria informed by current cosmetic science. Formulations that include supportive lipids, nourishing botanicals, fermented or postbiotic ingredients, and hydration-supportive systems may be classified within our skin compatibility framework.

Tier 1 · Strongest

Core Microbiome-Friendly Formulations

These formulations meet three or four of the framework criteria and represent ISUN’s most comprehensive microbiome-friendly formulations. Combining nutrient-rich botanicals, supportive lipids and natural actives, they reflect our approach to nurturing healthy-looking, resilient skin.

Best Overall ISUN Phyto-Antioxidant Moisturizing Cream

Facial Cream

Phyto-Antioxidant

A nutrient-rich moisturizing cream combining barrier-supportive oils, botanicals, Leuconostoc/radish root ferment, Symglucan, humectants, and vitamins C + E to support skin vitality, comfort, and resilience.

✓✓ Barrier Oils ✓✓ Botanicals ✓ Postbiotic ✓✓ Prebiotic

Ideal for: maturing skin, barrier support, daily restoration

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Postbiotic · Gen 2 ISUN Phyto-Infusion Serum

Facial Serum

Phyto-Infusion Serum

A microbiome-supportive serum featuring Saccharomyces lysate, Lactobacillus ferment, Symglucan, niacinamide, Ceramide NP, hyaluronic acid, centella, green tea, licorice, and vitamin C to support hydration, barrier resilience, and a balanced-looking complexion.

✓ Barrier Oils ✓✓ Botanicals ✓✓ Postbiotic ✓✓ Prebiotic

Ideal for: hydration support, barrier resilience, balanced-looking complexion

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Postbiotic Eye ISUN Phyto Eye Cream

Eye Cream

Phyto Eye Cream

A postbiotic and barrier-supportive eye formula with Saccharomyces lysate, Lactobacillus ferment/lysate, shea-derived lipids, squalane, hyaluronic acid, centella, chamomile, calendula, and vitamin C to support the delicate eye area.

✓✓ Barrier Oils ✓✓ Botanicals ✓✓ Postbiotic ✓ Prebiotic

Ideal for: fine lines, sensitivity, barrier repair

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Top Oil Score ISUN Ultra Ruby Facial Oil

Facial Oil

Ultra Ruby Facial Oil

A deeply nourishing facial oil rich in barrier-supportive plant oils and botanicals, ideal for dry, mature, or barrier-compromised skin.

✓✓ Barrier Oils ✓✓ Botanicals

Ideal for: dry skin, nourishment, barrier support

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Sensitive Skin ISUN Ultra Sapphire Facial Oil

Facial Oil

Ultra Sapphire Facial Oil

A gentle, calming facial oil with supportive lipids and soothing botanicals, ideal for sensitive-looking or redness-prone skin.

✓✓ Barrier Oils ✓✓ Botanicals

Ideal for: sensitivity, reactivity, compromised barriers

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Tier 2 · Strong

Supporting Formulations

Focused and purposeful, these formulations support specific aspects of skin health through nutrient-rich botanicals, supportive lipids and active ingredients. They offer complementary support within a microbiome-friendly skincare ritual.

ISUN Ultra Sunstone Facial Oil

Facial Oil

Ultra Sunstone Facial Oil

A lightweight facial oil suited to oily or combination skin, helping support comfort and balance without over-stripping.

✓✓ Barrier Oils ✓✓ Botanicals

Ideal for: oily and combination skin

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ISUN Sapphire Facial Oil

Facial Oil

Sapphire Facial Oil

A lightweight daily oil that helps nourish the skin while supporting softness, comfort and overall balance.

✓✓ Barrier Oils ✓✓ Botanicals

Ideal for: sensitive and combination skin

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ISUN Ruby Facial Oil

Facial Oil

Ruby Facial Oil

Rich in linoleic acid, this formulation helps support the skin's natural barrier while promoting a healthy-looking complexion.

✓✓ Barrier Oils ✓✓ Botanicals

Ideal for: dry skin, barrier repair

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ISUN Skin Restore Body Oil

Body Oil

Skin Restore Body Oil

A nourishing body oil with sunflower, rosehip, jojoba, and other plant oils to support body skin softness, comfort, and barrier care.

✓✓ Barrier Oils ✓✓ Botanicals

Ideal for: body care, barrier support

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ISUN Soothing Relief Balm

Face & Body Balm

Soothing Relief Balm

A targeted comfort balm with beta-glucan and soothing botanicals to support sensitive-looking, reactive, or visibly stressed skin.

✓✓ Botanicals ✓✓ Prebiotic

Ideal for: sensitivity, redness, recovery

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ISUN Soothing Silk Lotion

Body Lotion

Soothing Silk Lotion

A hydration-supportive body lotion with humectants, botanical extracts, and barrier-supportive oils. Best positioned for body hydration and comfort.

✓✓ Barrier Oils ✓✓ Botanicals ✓ Hydration

Ideal for: daily body hydration and comfort

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Consistent. Considered. Fully aligned with the intelligence of living skin.